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The Gut-Hormone Connection Explained

Writer's picture: Dr. Francesca Medina, NDDr. Francesca Medina, ND

Updated: 15 hours ago

Is Your Gut Messing with Your Hormones?


Let me tell you a little secret that most people (even some doctors) overlook: your gut health plays a HUGE role in your hormones.


If you've been dealing with irregular periods, acne that just won’t quit, PMS from hell, or that dreaded "mystery weight gain," you might be blaming your ovaries, your thyroid, or even your genetics.


But what if the real issue isn’t your hormones themselves—it’s your gut?


That’s right. Your digestive system isn’t just about breaking down food and absorbing nutrients. It’s a major player in detoxing excess hormones, reducing inflammation, and keeping your body in balance.


When your gut isn’t happy, your hormones aren’t happy either.


So let’s break this down. How exactly does your gut impact your hormones? And more importantly, what can you do to fix it?


What's in this article?



Woman in athletic wear makes heart shape on her stomach. Text: The Gut-Hormone Connection Explained. Dr. Francesca Medina, Naturopathic Doctor.

Case Study 1: When Gut Issues Cause Estrogen Overload


Meet Sarah. She’s 32, eats what she thinks is a healthy diet, and exercises regularly.


But she’s struggling with:

✅ Painful, heavy periods

✅ Breast tenderness before her cycle

✅ Stubborn weight gain (especially around her hips and thighs)

✅ Occasional bloating and constipation


After running a few tests, we discovered Sarah was dealing with estrogen dominance—meaning she had more estrogen in her system than her body could properly detox.


The problem? Her gut wasn’t eliminating estrogen efficiently.


How does gut health affect estrogen?

  • Your gut microbiome contains special bacteria (called the estrobolome) that help break down and remove excess estrogen.

  • If your gut is sluggish (hello, constipation) or overrun with bad bacteria, estrogen recirculates instead of being flushed out.

  • The result? Hormonal chaos.


How we fixed it:

  • Upped her fiber intake with flaxseeds, leafy greens, and chia seeds

  • Took a high-quality probiotic to rebalance her gut bacteria

  • Started daily walks and deep breathing to lower stress (because stress = gut inflammation!)

  • Cut back on alcohol and processed sugar, which were feeding bad gut bacteria


The result?

Within three months, her bloating was gone, her periods were lighter and less painful, and she finally lost the weight she’d been stuck with for years.


Case Study 2: Leaky Gut & The PCOS Connection


Now let’s talk about Rachel. She’s 28, has been diagnosed with PCOS, and is constantly battling:

✅ Acne along her jawline

✅ Insulin resistance (blood sugar crashes & sugar cravings)

✅ Fatigue, brain fog, and mood swings

✅ Gas, bloating, and food sensitivities


Rachel’s main issue?

Leaky gut—a condition where tiny gaps in the gut lining allow undigested food particles and toxins to sneak into the bloodstream, triggering inflammation. And guess what? Inflammation is a major driver of PCOS symptoms.


How does gut inflammation mess with hormones?

  • It spikes cortisol, which makes you feel constantly tired but wired.

  • It disrupts insulin sensitivity, making blood sugar control a nightmare.

  • It slows down the liver’s ability to detox estrogen, leading to acne and irregular cycles.


How we healed Rachel's gut:

  • Cut out gluten and dairy (both were triggering gut inflammation for her)

  • Focused on gut-healing foods like bone broth, collagen, and L-glutamine

  • Added fermented foods like kimchi and sauerkraut for beneficial bacteria

  • Took a digestive enzyme before meals to help break down food properly


The result?

Within 5 months, Rachel’s acne cleared up, her cravings disappeared, and her cycle regulated for the first time in years.



Is Your Gut Messing with Your Hormones? Signs to Watch For


If any of these sound familiar, your gut might be the culprit behind your hormonal struggles:

Bloating, constipation, or diarrhea (Your gut isn’t clearing out excess hormones)

PMS or heavy periods (Estrogen dominance linked to poor gut detox)

Hormonal acne (Inflammation from leaky gut)

Mood swings, anxiety, or brain fog (Gut imbalances affect serotonin levels)

Weight gain or blood sugar crashes (Gut health impacts insulin sensitivity)


How to Fix Your Gut & Restore Hormonal Balance


1. Get Things Moving (No More Constipation!)

  • Eat more fiber-rich foods (flaxseeds, chia seeds, leafy greens)

  • Drink at least 2L of water per day

  • Add magnesium citrate if you need extra help


2. Heal Your Gut Lining

  • Add gut-healing foods: bone broth, collagen, L-glutamine

  • Avoid gut irritants like gluten, dairy, processed sugar, and excessive alcohol

  • Reduce stress (yes, stress damages the gut lining too!)


3. Feed Your Good Gut Bacteria

  • Eat fermented foods like kimchi, sauerkraut, and kefir

  • Take a high-quality probiotic

  • Eat a variety of prebiotic foods (bananas, asparagus, garlic)


4. Balance Blood Sugar for Hormone Stability

  • Prioritize protein, fiber, and healthy fats with every meal

  • Avoid processed carbs and excessive caffeine, which spike cortisol

  • Try walking after meals to improve insulin sensitivity


Heal Your Gut, Heal Your Hormones


Your gut health isn’t just about digestion—it’s the foundation for balanced hormones.


If you’ve been struggling with acne, irregular periods, PMS, or fatigue, don’t overlook your gut.


Addressing gut health can lead to profound changes in your overall well-being, from better digestion and clearer skin to stabilized moods and more predictable cycles.


✅ Support your digestion

✅ Heal your gut lining

✅ Feed the good bacteria

✅ Balance blood sugar


Remember, healing doesn’t happen overnight, but small, consistent changes can transform your health over time.


Need a personalized plan? Book a consultation with me, and let’s get your gut and hormones back on track!



 


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As a dedicated Naturopathic Doctor, I invite you to schedule a personalized 1-on-1 appointment with me. Click here for more information on how to book your appointment.


My goal is to empower you to make your lifestyle your medicine, so I encourage you to take the first step by scheduling an appointment with me. However, if you are not in the space to make an appointment with me, I encourage you to explore my health articles and e-books. Also, be sure to sign up for my newsletter to get my naturopathic tips straight to your inbox.

*Dr. Francesca works only with patients physically located in California.*


*Disclaimer: Although I am a doctor, I may not be your doctor. The information contained within the pages of this site is for educational purposes only and should not be used to treat conditions. Please consult with your doctor before implementing any of the treatments, diets, supplements, etc. mentioned in this blog.*

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